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Ethical Considerations on Using Human Biologicals in Research

Human whole blood is a combination of human red blood cells (RBCs), various other cells , and plasma . For various experiments and research projects, these human biological s are needed in order to come up with the research objectives and to provide a solution for any problem that is prevailing or that concerns the human body in general.  However, no matter how much important is any research. There are ethical issues that need to be addressed before going further into the research. Why are these considerations important? Ethical considerations govern the process and are needed for the betterment of the research and of the society as well. These considerations are important because they allow us to do something that is right and use our resources for the better tomorrow of the human race. There have been many mishaps in the past where researchers were not bound to follow these ethical rules and as a result, they committed some serious moral crimes. The benefit of ethics is to te

Amish Mutation Protects Against Diabetes and May Extend Life

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The clinic parking lot in Berne, Ind., where some of the Amish residents carry a genetic mutation that may have life-extending benefits. Credit Courtesy of Indiana Hemophilia & Thrombosis Center Amish people living in a rural part of Indiana have a rare genetic mutation that protects them from Type 2 diabetes and appears to significantly extend their life spans, according to a new study. The findings, published on Wednesday in the journal Science Advances, shed light on the processes underlying cellular aging and could lead to new therapies for chronic diseases, some experts say. The researchers are planning at least one follow-up trial that will recreate the effects of the mutation so they can study its impact on obese people with insulin resistance, a precursor to diabetes. The mutation described in the new paper affects a mysterious protein called plasminogen activator inhibitor-1, or PAI-1, that is known primarily for its role in promoting blood clotting. The mutation was fi

Marketing Manager

Emerging biotech company located in Novi, MI is seeking a Marketing Manager to lead the marketing and web operations of the business. The position is for a permanent employee who wants to grow with the company.   Characteristics necessary for you to be successful in this position: •    Ability to work closely with a small team. •    A minimum of 2 years of experience as a Marketing Manager at a small to medium-sized company. •    Team player with a positive and respectful attitude. Skills necessary for you to be successful in this position: •    Professional experience with Microsoft Word, Excel, Outlook, Adobe Photoshop, Illustrator, and InDesign. •    Ability to write, edit, and proofread marketing copy. •    Ability to use HTML for creating marketing emails and newsletters. •    Experience editing and updating websites through CMS, or capability to learn. •    General knowledge of Google AdWords and Analytics. We operate with a small team. You must be

The Research Process Involving Human and Animal Biologicals

What Are Biologicals? Biologicals can be defined as pharmacological products utilized in healthcare research, diagnosis and prevention for treatment of diseases and observation of change in behavior of several different cells under different circumstances, when they come in come in contact with various biological agents. Biologicals are gathered from live cells or tissues like sera, vaccine, recombinant products, etc. and are used for potential therapeutic, diagnostics and research applications. Medical and healthcare research, be it on animals or humans, requires the utilization of biologicals. Biologicals can be originated from animals such as animal blood , animal plasma , animal serum and animal tissues. Animal biological products for research purposes can be obtained from a wide range of animal species. Although, the human biological specimens such as human serum, human whole blood, etc., that used in research, originate from human bodies but are no longer a part of a liv

The Significance of Harvesting Fetal Bovine Serum in Animal Biologicals

FBS, otherwise known as, Fetal Bovine Serum is fetal serum from a calf and is blood that is fractioned and remains once the blood is naturally coagulated and separated from the red blood cells by centrifugation. Fetal bovine serum is a product that is utilized in laboratories for research purposes. It is a blood product which surpasses cell culture testing standards and, therefore, is extensively used to promote growth medium. First Step in Process FBS is a dairy industry by-product. Just like the majority of other animal serum utilized in cell culture, Fetal Bovine Serum, is created from blood collected from commercial slaughterhouses. The first step of FBS production is the harvesting of blood from a bovine fetus with the help of a closed and isolated selection system. A cardiac puncture is performed on a calf’s fetus during slaughter and the blood is drawn from the bovine fetus after the fetus is removed from cow that has been killed. The blood is refrigerated so that it will

The Importance of Human Serum

The human blood is comprised of several important parts all with different purposes. Human blood is made up of plasma, human serum, red blood cells and white blood cells. Red blood cells are the cells that carry oxygen to all parts in the body while white blood cells are the cells that fight against diseases and foreign bodies. Plasma and human serum are similar but the greatest difference is the clotting factors. Fibrinogen is a substance that is essential for blood clotting to take place. When human serum and plasma are separated from the blood, plasma retains the fibrinogen element while human serum constitutes the part of blood without fibrinogen. Human serum thus constitutes water which is dissolved with hormones, minerals, proteins and carbon dioxide. Human serum is an important source of electrolytes. Why is human blood split up? When an individual donates blood, this blood is separated into different parts so that it can be given to different patients with specific